Functional Characterization of the Drosophila Hmt4-20/Suv4-20 Histone Methyltransferase
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چکیده
منابع مشابه
Functional characterization of the Drosophila Hmt4-20/Suv4-20 histone methyltransferase.
Di- and trimethylation of histone H4 lysine20 (H4K20) are thought to play an important role in controlling gene expression in vertebrates and in Drosophila. By inducing a null mutation in Drosophila Suv4-20, we show that it encodes the histone H4 lysine20 di- and trimethyltransferase. In Suv4-20 mutants, the H4K20 di- and trimethyl marks are strongly reduced or absent, and the monomethyl mark i...
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ژورنال
عنوان ژورنال: Genetics
سال: 2008
ISSN: 1943-2631
DOI: 10.1534/genetics.108.087650